You can find a full list of our publications here.
Our analysis code is available on GitHub.
Some key recent papers
Mavrommatis C, Belsky DW, Ying K, Moqri M, Campbell A, Richmond A, Gladyshev VN, Chandra T, McCartney DL, Marioni RE. An unbiased comparison of 14 epigenetic clocks in relation to 10-year onset of 174 disease outcomes in 18,859 individuals. medRxiv [Preprint]. 2025 Jul 15:2025.07.14.25331494.
Our analysis code is available on GitHub.
Some key recent papers
Mavrommatis C, Belsky DW, Ying K, Moqri M, Campbell A, Richmond A, Gladyshev VN, Chandra T, McCartney DL, Marioni RE. An unbiased comparison of 14 epigenetic clocks in relation to 10-year onset of 174 disease outcomes in 18,859 individuals. medRxiv [Preprint]. 2025 Jul 15:2025.07.14.25331494.
Robertson JA, Bajzik J, Vernardis S, Chybowska AD, McCartney DL, Grauslys A, Mur J, Smith HM, Campbell A, Drake C, Grant H, Pearce J, Russ TC, Adkin P, White M, Brigden C, Messner CB, Porteous DJ, Hayward C, Cox SR, Zelezniak A, Ralser M, Robinson MR, Marioni RE. Methylome-wide association studies and epigenetic biomarker development for 133 mass spectrometry-assessed circulating proteins in 14,671 Generation Scotland participants. Genome Biol. 2025 Dec 8;26(1):417.
Conole ELS, Robertson JA, Smith HM, Cox SR, Marioni RE. Epigenetic clocks and DNA methylation biomarkers of brain health and disease. Nat Rev Neurol. 2025 Aug;21(8):411-421.
Chybowska AD, Bernabeu E, Yousefi P, Suderman M, Hillary RF, Clark R, MacGillivray L, Murphy L, Harris SE, Corley J, Campbell A, Spires-Jones TL, McCartney DL, Cox SR, Price JF, Evans KL, Marioni RE. (2025) A blood- and brain-based EWAS of smoking. Nat Commun.16(1): 3210.
Conole ELS, Robertson JA, Smith HM, Cox SR, Marioni RE. Epigenetic clocks and DNA methylation biomarkers of brain health and disease. Nat Rev Neurol. 2025 Aug;21(8):411-421.
Chybowska AD, Bernabeu E, Yousefi P, Suderman M, Hillary RF, Clark R, MacGillivray L, Murphy L, Harris SE, Corley J, Campbell A, Spires-Jones TL, McCartney DL, Cox SR, Price JF, Evans KL, Marioni RE. (2025) A blood- and brain-based EWAS of smoking. Nat Commun.16(1): 3210.
Bernabeu E, Chybowska AD, Kresovich JK, Suderman M, McCartney DL, Hillary RF, Corley J, Valdés-Hernández MDC, Maniega SM, Bastin ME, Wardlaw JM, Xu Z, Sandler DP, Campbell A, Harris SE, McIntosh AM, Taylor JA, Yousefi P, Cox SR, Evans KL, Robinson MR, Vallejos CA, Marioni RE. (2025) Blood-based epigenome-wide association study and prediction of alcohol consumption. Clin Epigenetics. 17(1): 14.
Smith HM, Ng HK, Moodie JE, Gadd DA, McCartney DL, Bernabeu E, Campbell A, Redmond P, Taylor A, Page D, Corley J, Harris SE, Tay D, Deary IJ, Evans KL, Robinson MR, Chambers JC, Loh M, Cox SR, Marioni RE, Hillary RF. (2025) DNA methylation-based predictors of metabolic traits in Scottish and Singaporean cohorts. Am J Hum Genet. 112(1): 106-115.
Smith HM, Moodie JE, Monterrubio-Gómez K, Gadd DA, Hillary RF, Chybowska AD, McCartney DL, Campbell A, Redmond P, Page D, Taylor A, Corley J, Harris SE, Valdés Hernández M, Muñoz Maniega S, Bastin ME, Wardlaw JM, Deary IJ, Boardman JP, Mullin DS, Russ TC, Cox SR, Marioni RE. (2024) Epigenetic scores of blood-based proteins as biomarkers of general cognitive function and brain health. Clin Epigenetics. 16(1): 46.
Hillary RF, Ng HK, McCartney DL, Elliott HR, Walker RM, Campbell A, Huang F, Direk K, Welsh P, Sattar N, Corley J, Hayward C, McIntosh AM, Sudlow C, Evans KL, Cox SR, Chambers JC, Loh M, Relton CL, Marioni RE, Yousefi PD, Suderman M. (2024) Blood-based epigenome-wide analyses of chronic low-grade inflammation across diverse population cohorts. Cell Genom. 4(5): 100544.
Hillary RF, Gadd DA, Kuncheva Z, Mangelis T, Lin T, Ferber K, McLaughlin H, Runz H; Biogen Biobank Team; Marioni RE, Foley CN, Sun BB. (2024) Systematic discovery of gene-environment interactions underlying the human plasma proteome in UK Biobank. Nat Commun. 15(1): 7346.
Gadd DA, Smith HM, Mullin D, Chybowska O, Hillary RF, Kimenai DM, Bernabeu E, Cheng Y, Fawns-Ritchie C, Campbell A, Page D, Taylor A, Corley J, Del C Valdés-Hernández M, Maniega SM, Bastin ME, Wardlaw JM, Walker RM, Evans KL, McIntosh AM, Hayward C, Russ TC, Harris SE, Welsh P, Sattar N, Cox SR, McCartney DL, Marioni RE. (2024) DNAm scores for serum GDF15 and NT-proBNP levels associate with a range of traits affecting the body and brain. Clin Epigenetics. 16(1): 124.
Chybowska AD, Gadd DA, Cheng Y, Bernabeu E, Campbell A, Walker RM, McIntosh AM, Wrobel N, Murphy L, Welsh P, Sattar N, Price JF, McCartney DL, Evans KL, Marioni RE. (2024) Epigenetic Contributions to Clinical Risk Prediction of Cardiovascular Disease. Circ Genom Precis Med. 17(1): e004265.
Gadd DA, Hillary RF, Kuncheva Z, Mangelis T, Cheng Y, Dissanayake M, Admanit R, Gagnon J, Lin T, Ferber KL, Runz H; Biogen Biobank Team; Foley CN, Marioni RE, Sun BB. (2024) Blood protein assessment of leading incident diseases and mortality in the UK Biobank. Nat Aging. 4(7): 939-948.